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- 2026年08月13日
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- 文献和实验
- 技术资料
- 保质期：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 保存条件：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 英文名：
TSLP R
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ¥741.00 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ¥2210.00 |
| 规格： | 500ug | 产品价格： | ¥15840.00 |
| 规格： | 1mg | 产品价格： | ¥23760.00 |
| 基因名 | TSLP R |
| 别名 | CRL2; CRL2cytokine receptor CRL2 precusor; CRLF2; CRLF2Y; CRLM-2; Cytokine receptor-like 2; cytokine receptor-like factor 2; ILXR; IL-XR; P2RY8/CRLF2 fusion; PCOR1; TSLP R; TSLP receptor; TSLPR |
| 蛋白号 | Q9HC73 |
| 种属 | Human |
| 宿主 | HEK293 |
| 产品描述 | Recombinant Human CRLF2 is produced by our Mammalian expression system and the target gene encoding Gly25-Lys231 is expressed with a human IgG1 Fc tag at the C-terminus. |
| 区间范围 | Gly25-Lys231 |
| 标签信息 | C-Fc |
| 预测分子量 | 60-80 kDa |
| 表观分子量 | 60-80 KDa, reducing conditions |
| 纯度 | ≥95% by SDS‐PAGE. |
| 内毒素 | <1EU/ug as determined by LAL test. |
| 溶剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 | Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: 2-8°C for 2-7 days under sterile conditions after redissolves; -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; -20°C to -70℃ for 12 months in lyophilized state. |
| 运输条件 | 冷冻运输 |
| 背景说明 | Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system. TSLP R expression is ubiquitous in the immune and hematopoietic cells, but is up-regulated in Th2-skewed cells. Cells expressing TSLP R alone bind TSLP with low affinity. Co-expression of TSLP R and IL-7 R alpha is required for high-affinity TSLP binding and signal transduction . The TSLP R and IL-7 R alpha are coexpressed primarily on monocytes and dendritic cells and at lower levels in lymphoid cells. TSLP has been shown to induce the release of T cell-attracting chemokines from monocytes and enhance the maturation of CD11c+ dendritic cells. |
| 细胞活性 | No activity experimental data, to be verified. |
| ELISA活性 | Immobilized Human TSLP at 10μg/ml (100μl/wel) can bind Human TSLP R-Fc .The ED50 of Human TSLP R-Fc is 0.16 ug/ml. |
| SPR/BLI活性 | Loaded Human TSLP-His on HIS1K Biosensor, can bind Human TSLP R-Fc with an affinity constant of 37.97 nM as determined in BLI assay. |
| 研究领域 | 生物制药相关研究 |
| 英文名称 | TSLP R |
| 中文名称 | TSLP R蛋白 |
| 单位 | 支 |
| 规格 | 10ug ; 50ug ; 500ug ; 1mg |
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