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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥24960.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥16644.0 |
| 规格: | 50ug | 产品价格: | ¥2210.0 |
| 规格: | 10ug | 产品价格: | ¥741.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Angiopoietin-related protein 4;425O18-1;Angiopoietin-like protein 4;Fasting-induced adipose factor;Hepatic fibrinogen/angiopoietin-related protein;HFARP;Secreted protein Bk89;Angptl4;Farp;Fiaf;Ng27 |
| 中文名称 | Recombinant Cynomolgus GITR Ligand/TNFSF18 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | TNFSF18 is a single-pass type II membrane protein.It is expressed at high levels in the small intestine,ovary,testis,kidney and endothelial cells.TNFSF18 cytokine binds to TNFRSF18/AITR/GITR.It regulates T-cell responses,and functions as costimulator and lower the threshold for T-cell activation and T-cell proliferation.It is Important for interactions between activated T-lymphocytes and endothelial cells and Promotes leukocyte adhesion to endothelial cells.TNFSF18 mediates activation of NF-kappa-B.As Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1.It also regulates migration of monocytes from the splenic reservoir to sites of inflammation. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验的关系理不出头绪。GSK-3 beta 总蛋白减少,p-GSK-3 beta (ser 9)增加,是不是足以说明有活性的GSK-3 beta 减少更多,这样理解不知道对不对,希望给以指点。 galaxy22 楼主你好,请问你做出结果的tyr216的抗体是哪个公司的。。。我做出来总量是减少的,active B catenin是减少的,那我有必要做ser9 和tyr216的磷酸化形式吗?我想研究wnt和akt。。。 棉花糖的温柔
() #交换 x 轴和 y 轴> p + ylim(0,15) #如果想截取某一段可以用此命令设置值域。> p + scale_x_continuous(breaks =seq(18,34,50) ) #设置刻度线位置> p + theme(axis.text.x = element_text(angle = 90,family = "Times",face = "italic",colour = "darkred",size=rel(0.9))) # angle = 90 设置字体角度, family
膜蛋白的重要性不言而喻,假如细胞膜是守护细胞的城墙,而膜蛋白就是站在城墙上的各司其职的士兵,肩负着把守城门、传递信号、运输物质等重要职责。膜蛋白 一旦“失守”,就会造成细胞功能紊乱,进而引起组织和器官发生病变,使身体遭受病痛侵扰。这也就是为什么膜蛋白成为大多数重要的药物研究对象和靶点。在人体蛋白中,有大约30%是膜蛋白,FDA批准的新药中,绝大多数都以膜蛋白为靶点,几乎所有的膜蛋白都是研究热点。然而让人吃惊的是,乐观估计,目前已经被透彻研究清楚结构的膜蛋白仅占膜蛋白总量的1%。究其原因,是因为
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