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- 2026年08月13日
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- 文献和实验
- 技术资料
- 保质期：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 保存条件：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 英文名：
PD-L2
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ¥764.00 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ¥2293.00 |
| 规格： | 500ug | 产品价格： | ¥10349.00 |
| 规格： | 1mg | 产品价格： | ¥14784.00 |
| 基因名 | PD-L2 |
| 别名 | Programmed Cell Death 1 Ligand 2; PD-1 Ligand 2; PD-L2; PDCD1 Ligand 2; Programmed Death Ligand 2; Butyrophilin B7-DC; B7-DC; CD273; PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2 |
| 蛋白号 | A4GW30 |
| 种属 | Cynomolgus |
| 宿主 | HEK293 |
| 产品描述 | Recombinant Cynomolgus Programmed Cell Death Ligand 2 is produced by our Mammalian expression system and the target gene encoding Leu20-Pro219 is expressed with a 6His tag at the C-terminus. |
| 区间范围 | Leu20-Pro219 |
| 标签信息 | C-6His |
| 预测分子量 | 30-40 kDa |
| 表观分子量 | 30-40 KDa, reducing conditions |
| 纯度 | ≥95% by SDS‐PAGE. |
| 内毒素 | <1EU/ug as determined by LAL test. |
| 溶剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 复溶 | Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 | Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: 2-8°C for 2-7 days under sterile conditions after redissolves; -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; -20°C to -70℃ for 12 months in lyophilized state. |
| 运输条件 | 冷冻运输 |
| 背景说明 | Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| 细胞活性 | No activity experimental data, to be verified. |
| ELISA活性 | No activity experimental data, to be verified. |
| SPR/BLI活性 | No activity experimental data, to be verified. |
| 研究领域 | 生物制药相关研究 |
| 英文名称 | PD-L2 |
| 中文名称 | PD-L2蛋白 |
| 单位 | 支 |
| 规格 | 10ug ; 50ug ; 500ug ; 1mg |
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文献和实验11b/CD3/CD20/CD57 同时进行免疫荧光组化染色，并使用 Vectra 多光谱成像系统自动获取 8 通道 肿瘤组织芯片图像（下图 b），最后使用 InForm 定量分析软件，分别对 PD-L1 和另外 6 种免疫细胞标志物双阳性的免疫细胞群进行分析，发现肝癌组织中肿瘤区域内的 CD68 阳性巨噬细胞（Microphages, M φs）和肿瘤细胞（Tumor Cells, TCs）在 PD-L1 表达谱中具有最高的相关性（下图 c）。为研究 PD-L1 表达谱与巨噬细胞的相关性，文章中继续使用
Expression of Recombinant Cytochromes c in E. coli
for proper folding and stability. However, significant advances in expression of recombinant cytochromes c have been made during the last decade. It has been shown that a single gene cluster, ccmA–H , is responsible for cytochrome c maturation in Escherichia
另外 3 个克隆，其对免疫细胞的染色更为突出[4]。PD-L1 诊断抗体比较结果Abcam[28-8] 与市面上 C 公司 PD-L1 诊断抗体进行对比测试，通过实验结果表现看出，28-8 与 SP142 有更高的特异性与灵敏度。> Abcam[28-8] 和 C 公司 PD-L1 诊断抗体对比：图 1：Abcam[28-8] 和 C 公司 PD-L1 诊断抗体在 L2987 以及 ES-2 细胞中的染色特征比较结果[3]如图 1，Abcam[28-8] VS C 公司 PD-L1 诊断抗体，数据
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