- ￥520 - 14400
- Solarbio
- P00516
- 北京
- 2025年07月25日
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥14400.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥10080.0 |
| 规格： | 50ug | 产品价格： | ￥1664.0 |
| 规格： | 10ug | 产品价格： | ￥520.0 |
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts
成员:Zhao Qin, Su Hong, Jiang Wei, Luo Haodong, Pan Lu, Liu Yuan, Yang Ce, Yin Ying, Yu Lehua, Tan Botao
论文因子:4.4 发表期刊:NEUROCHEMICAL RESEARCH pmid:37395917
| 基本信息 | |
| 基因名 | |
| 别名 | Osteopontin;Bone Sialoprotein 1;Nephropontin;Secreted Phosphoprotein 1;SPP-1;Urinary Stone Protein;Uropontin;SPP1;BNSP;OPN |
| 中文名称 | Recombinant Human Osteopontin/OPN/SPP-1/SPP1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Secreted Phosphoprotein 1 (SPP1) is a secreted multifunctional glycoprotein.Its putative functions include roles in bone metabolism，immune regulation，wound healing，cell survival，and tumor progression.Based on gene structure and chromosomal location，SPP1 is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family that also includes bone sialoprotein (BSP)，dentin matrix protein 1 (DMP1)，dentin sialophosphoprotein (DSPP)，enamelin (ENAM)，and matrix extracellular phosphoglycoprotein (MEPE).SPP1 is expressed in bone，although it is also expressed in other tissues.SPP1 acts as a cytokine that is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10.It is essential in the pathway that leads to type I immunity.Osteopontin has been implicated as an important factor in bone remodeling.Specifically，research suggests it plays a role in anchoring osteoclasts to the mineral matrix of bones.The fact that SPP1 interacts with multiple cell surface receptors which are ubiquitously expressed makes it an active player in many physiological and pathological processes including wound healing，bone turnover，tumorigenesis，inflammation and ischemia.Therefore，manipulation of plasma Osteopontin levels may be useful in the treatment of autoimmune diseases，cancer metastasis，osteoporosis and some forms of stress. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts
成员:Zhao Qin, Su Hong, Jiang Wei, Luo Haodong, Pan Lu, Liu Yuan, Yang Ce, Yin Ying, Yu Lehua, Tan Botao
论文因子:4.4 发表期刊:NEUROCHEMICAL RESEARCH pmid:37395917
的关系理不出头绪。GSK-3 beta 总蛋白减少，p-GSK-3 beta (ser 9)增加，是不是足以说明有活性的GSK-3 beta 减少更多，这样理解不知道对不对，希望给以指点。 galaxy22 楼主你好，请问你做出结果的tyr216的抗体是哪个公司的。。。我做出来总量是减少的，active B catenin是减少的，那我有必要做ser9 和tyr216的磷酸化形式吗？我想研究wnt和akt。。。 棉花糖的温柔
Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
() #交换 x 轴和 y 轴> p + ylim(0,15) #如果想截取某一段可以用此命令设置值域。> p + scale_x_continuous(breaks =seq(18,34,50) ) #设置刻度线位置> p + theme(axis.text.x = element_text(angle = 90,family = "Times",face = "italic",colour = "darkred",size=rel(0.9))) # angle = 90 设置字体角度, family
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