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- Solarbio
- P00660
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥17280.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥12096.0 |
| 规格： | 50ug | 产品价格： | ￥1872.0 |
| 规格： | 10ug | 产品价格： | ￥780.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Cluster of Differentiation 74;CD74 antigen;CD74 molecule,major histocompatibility complex,class II invariant chain;DHLAG gamma chain of class II antigens;HLA class II histocompatibility antigen gamma chain;HLADG;HLA-DR antigens-associated invariant chain;HLA-DR-gamma;Ia antigen-associated invariant chain;Ia-associated invariant chain;Ia-GAMMA;MHC HLA-DR gamma chain;CD74;DHLAG;HLADG;Ia-gamma;INVG34; |
| 中文名称 | Recombinant Mouse HLADG/CD74 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Mouse HLA class II histocompatibility antigen gamma chain (CD74)，is a single-pass type II membrane glycoprotein which contains 1 thyroglobulin type-1 domain.Mouse CD74 shares 75% and 88% aa sequence identity with human and rat CD74，respectively.CD74 plays an important role in adaptive immunity，inflammation，and cancer.It plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.CD74 also associates with CD44 and binds with high affinity to the cytokine MIF，leading to inflammatory leukocyte responses，protection from tissue fibrosis，B cell proliferative and survival signaling，and the up-regulation of angiogenic factors in endometrial stromal cells. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Mouse Strains and Genetic Nomenclature
. Biol. J. Linnean Soc. 30:51‐58. Bulfield, G., Siller, W.G., Wight, P.A., and Moore, K.J. 1984. X chromosome‐linked muscular dystrophy (mdx) in the mouse. Proc. Natl. Acad
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