P00442 Recombinant Human NRG1-
beta 1/HRG1-beta 1 EGF Domain/Neuregulin 1/NRG1 beta 1 EGF Domain/Neuregulin1 beta 1/Neuregulin-1 细胞因子/蛋白- ￥520 - 10080
- Solarbio
- P00442
- 北京
- 2025年07月25日
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- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥10080.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥6240.0 |
| 规格： | 50ug | 产品价格： | ￥1092.0 |
| 规格： | 10ug | 产品价格： | ￥520.0 |
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:ErbB4 promotes M2 activation of macrophages in idiopathic pulmonary fibrosis
成员:Yu Jiang, Jialin Shi, Junhao Zhou, Chunxiao He, Ruinan Gu
论文因子:2.2 发表期刊:Open Life Sciences pmid:37800117
| 基本信息 | |
| 基因名 | |
| 别名 | Pro-neuregulin-1;Neuregulin-1 beta 1;NRG1-beta 1;HRG1-beta 1;EGF;NRG1;GGF;HGL;HRGA;NDF;SMDF; |
| 中文名称 | Recombinant Human NRG1-beta 1/HRG1-beta 1 EGF Domain/Neuregulin 1/NRG1 beta 1 EGF Domain/Neuregulin1 beta 1/Neuregulin-1 beta 1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS，pH7.4. |
| 纯度 | ≥90% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | neuregulin-1 (heregulin-1，NRG1) is a member of neuregulin family，which is comprised of four genes that encode a large number of secreted or membrane-bound isoforms.All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors.NRG1 isoforms can be classified into type I，type II and type III isoforms.NRG1 directs ligand for ERBB3 and ERBB4 tyrosine kinase receptors，concomitantly recruits ERBB1 and ERBB2 coreceptors，resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors.NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:ErbB4 promotes M2 activation of macrophages in idiopathic pulmonary fibrosis
成员:Yu Jiang, Jialin Shi, Junhao Zhou, Chunxiao He, Ruinan Gu
论文因子:2.2 发表期刊:Open Life Sciences pmid:37800117
的关系理不出头绪。GSK-3 beta 总蛋白减少，p-GSK-3 beta (ser 9)增加，是不是足以说明有活性的GSK-3 beta 减少更多，这样理解不知道对不对，希望给以指点。 galaxy22 楼主你好，请问你做出结果的tyr216的抗体是哪个公司的。。。我做出来总量是减少的，active B catenin是减少的，那我有必要做ser9 和tyr216的磷酸化形式吗？我想研究wnt和akt。。。 棉花糖的温柔
Introduction of human 14-3-3 proteins
----------------------------------------------------------------------------A binding sequence for the 14-3-3 protein within the cytoplasmic domain of the adhesion receptor,platelet glycoprotein Ib alphaDu X; Fox JE; Pei SDepartment of Vascular Biology,Scripps Research Institute,La Jolla,California
after specifically interacting with its receptors. Human IL-2 is a 133-amino acid polypeptide with a molecular mass of 15-18 kDa. IL-2 signaling is mediated by a multichain receptor complex consisting of an alpha (CD25), beta (CD122), and gamma (CD132) chain. The IL
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