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P00593 Recombinant Human SLAMF

7/CD319/CRACC 细胞因子/蛋白
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  • ¥728 - 21120
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  • P00593
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2184.0
    规格:10ug产品价格:¥728.0
    基本信息
    基因名
    别名SLAM Family Member 7;CD2 Subset 1;CD2-Like Receptor-Activating Cytotoxic Cells;CRACC;Membrane Protein FOAP-12;Novel Ly9;Protein 19A;CD319;SLAMF7;CS1
    中文名称Recombinant Human SLAMF7/CD319/CRACC
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain.SLAMF7 is expressed in NK cells,activated B-cells,NK-cell line but not in promyelocytic,B-cell lines,or T-cell lines.Although the cytoplasmic domain of CS1 contains immunoreceptor tyrosine-based switch motifs (ITSM),which enables to recruite signaling lymphocyte activation molecule (SLAM)-associated protein (SAP/SH2D1A),it activates NK cells in the absence of a functional SAP.SLAMF7 positively regulated natural killer cell functions by a mechanism dependent on the adaptor EAT-2 but not the related adaptor SAP.However,in the absence of EAT-2,CRACC potently inhibited natural killer cell function.It was also inhibitory in T cells,which are typically devoid of EAT-2.Thus,SLAMF7 can exert activating or inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    ¥728 - 21120