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P00569 Recombinant Human Ubiqu

itin carboxyl-terminal hydrolase 14/USP14 细胞因子/蛋白
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  • ¥728 - 21120
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  • P00569
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2756.0
    规格:10ug产品价格:¥728.0
    基本信息
    基因名
    别名Ubiquitin Carboxyl-Terminal Hydrolase 14;Deubiquitinating Enzyme 14;Ubiquitin Thioesterase 14;Ubiquitin-Specific-Processing Protease 14;USP14;TGT
    中文名称Recombinant Human Ubiquitin carboxyl-terminal hydrolase 14/USP14
    外观(性状)Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 20% Glycerol, pH 8.0.
    纯度≥90% as determined by reducing SDS-PAGE.
    储存条件Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
    运输条件干冰运输
    背景说明Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains.USP14 located in the cytoplasm is a proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins.USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1.In addition,USP14 is indispensable for synaptic development and function at neuromuscular junctions,required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.
    来源E.coli
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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