P00098 Recombinant Human CXCL

【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】

标题:CHI3L1 signaling impairs hippocampal neurogenesis and cognitive function in autoimmune-mediated neuroinflammation

成员:Wei Jiang, Fan Zhu, Huiming Xu, Li Xu, Haoyang Li, Xin Yang, Shabbir Khan Afridi, Shuiqing Lai, Xiusheng Qiu, Chunxin Liu, Huilu Li, Youming Long, Yuge Wang, Kevin Connolly, Jack A. Elias, Chun Geun Lee, Yaxiong Cui, Yu-Wen Alvin Huang, Wei Qiu, Changyong

论文因子:13.6 发表期刊:Science Advances pmid:37756391

Recombinant Human C-X-C Motif Chemokine 1 is produced by our Mammalian expression system and the target gene encoding Ala35-Asn107 is expressed with a 6His tag at the C-terminus.

基本信息
基因名
别名	Growth-Regulated Alpha Protein;C-X-C Motif Chemokine 1;GRO-Alpha(1-73);Melanoma Growth Stimulatory Activity;MGSA;Neutrophil-Activating Protein 3;NAP-3;CXCL1;GRO;GRO1;GROA;MGSA;SCYB1
外观(性状)	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, pH 7.4.
纯度	≥95% as determined by reducing SDS-PAGE.
储存条件	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
背景说明	Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils.CXCL1 is expressed by macrophages，neutrophils and epithelial cells; it has neutrophil chemoattractant activity.CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons，and may induce long-term changes that involve protein synthesis.
来源	Human cells
溶剂	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素	Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
单位	支