P00549 Recombinant Human Cadherin-1/E-Cadherin/CDH1 细胞因子/蛋白

P00549 Recombinant Human Cadhe

rin-1/E-Cadherin/CDH1 细胞因子/蛋白
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  • ¥624 - 15360
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  • P00549
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥15360.0
    规格:500ug产品价格:¥10752.0
    规格:50ug产品价格:¥1560.0
    规格:10ug产品价格:¥624.0
    基本信息
    基因名
    别名Cadherin-1;CDH1;CAM 120/80;E-cadherin;CD324
    中文名称Recombinant Human Cadherin-1/E-Cadherin/CDH1
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明E-Cadherin is a classical member of the cadherin superfamily.The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats,a transmembrane region,and a highly conserved cytoplasmic tail.Mutations in this gene are correlated with gastric,breast,colorectal,thyroid,and ovarian cancers.Loss of function is thought to contribute to progression in cancer by increasing proliferation,invasion,and/or metastasis.The ectodomain of this protein mediates bacterial adhesion to mammalian cells,and the cytoplasmic domain is required for internalization.Identified transcript variants arise from mutation at consensus splice sites.Also,E-Cadherin has a potent invasive suppressor role and it is a ligand for integrin alpha-E/beta-7.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    ¥624 - 15360