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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥15360.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥10752.0 |
| 规格: | 50ug | 产品价格: | ¥1560.0 |
| 规格: | 10ug | 产品价格: | ¥624.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Small ubiquitin-related modifier 3;SUMO-3;SMT3 homolog 1;SUMO-2;Ubiquitin-like protein SMT3A;Smt3A |
| 中文名称 | Recombinant Human Small Ubiquitin-Related Modifier 3/SUMO3/SMT3A |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20℃ for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Small ubiquitin-like modifier (SUMO),also known as SUMO homologue and SMT3,is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way to alter their function,location,and/or half-life.Small ubiquitin-like modifiers include SUMO1,SUMO2,SUMO3,and SUMO4.Except for SUMO4,all other SUMOs are ubiquitously expressed,including in the brain.In human,SUMO2 and SUMO3 are two highly homologous proteins,collectively called SUMO2/3.Several studies suggest that SUMO3 are associated with pathogenesis in several neurological diseases,including Alzheimer's disease,Parkinson's disease,and cerebral ischemia/stroke. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Studies of the Ubiquitin Proteasome System
both in vitro and in cells. Because another protein modifier, NEDD8, itself regulates aspects of the ubiquitin system, basic protocols on neddylation are also included in this unit. Keywords: Ubiquitin; ubiquitylation; proteasomal degradation; protein
Many cytokines alter the half-lives and stabilities of mRNAs for other cytokines (1 ) and enzymes that may be related to disease progression. For example, IL-1β stabilizes the mRNA for human interstitial collagenase-1 in normal fibroblasts
Preparation of Sumoylated Substrates for Biochemical Analysis
Covalent modification of proteins with SUMO (small ubiquitin related modifier) affects many cellular processes like transcription, nuclear transport, DNA repair and cell cycle progression. Although hundreds of SUMO targets
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