P00331 Recombinant Mouse IFN gamma R1/CD119 细胞因子/蛋白

P00331 Recombinant Mouse IFN g

amma R1/CD119 细胞因子/蛋白
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  • ¥260 - 6240
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  • P00331
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥6240.0
    规格:500ug产品价格:¥4680.0
    规格:50ug产品价格:¥728.0
    规格:10ug产品价格:¥260.0
    基本信息
    基因名
    别名CD119;Interferon gamma receptor 1;IFNGR1;IFN-gamma receptor 1;IFN-gamma-R1;CD119 antigen;IFN gamma receptor 1;IFNGR;immune interferon receptor 1;interferon gamma receptor 1;interferon-gamma receptor alpha chain
    中文名称Recombinant Mouse IFN-gamma R1/CD119
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明The tetrameric receptor complex for IFNγ consists of two subunits,IFNGR1 (IFNγ Rα) and IFNGR2 (IFNγ Rβ),through which the dimeric IFN-γ exerts its biological functions,including antiviral,antiproliferation and immune-modulatory activity in mammals.Both IFNGR1 and IFNGR2 are single transmembrane proteins belonging to the class II cytokine family.FNGR1,widely expressed in most host cells,is essential for IFNγ binding,receptor trafficking,and signal transduction.IFNGR1 possesses an intracellular Janus tyrosine kinase (JAK) 1 binding site,a signal transducer and activator of transcription 1 (STAT1) binding site.The resulting STAT1 homodimers translocate from the cytoplasm to the nucleus and bind to the interferon-gamma activated sequence (GAS) promoter to induce expression of downstream interferon stimulated genes (ISGs).
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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