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- Solarbio
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- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥15360.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥10752.0 |
| 规格： | 50ug | 产品价格： | ￥1560.0 |
| 规格： | 10ug | 产品价格： | ￥676.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Programmed Cell Death 1 Ligand 1;PD-L1;PDCD1 Ligand 1;Programmed Death Ligand 1;B7 Homolog 1;B7-H1;CD274;B7H1;PDCD1L1;PDCD1LG1;PDL1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | CD274，also known as B7-H1 or programmed death ligand 1 (PD-L1)，is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily.Programmed death-1 ligand-1 (PD-L1，CD274，B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.By binding to PD1 on activated T-cells and B-cells，PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.Accordingly，it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers.PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| 单位 | 支 |
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，PD-1/PD-L1这么值钱，大家一定好奇它到底是什么鬼。 PD-1全名是程序性死亡分子1(programmed death-1)是Ishida等[1]通过消减杂交技术于1992年发现的[2]，是CD28家族成员，胞质区含有2个酪氨酸残基，1个位于靠近N端的免疫受体酪氨酸抑制基序(ITIM)中，另一个1个位于靠近C端的免疫受体酪氨酸转化基序(ITSM)中[2]。 PD-L1(CD274)是B7家族成员，是PD-1的配体，属于1型跨膜蛋白，全长290个氨基酸，包含1个IgV样
578475733 因最近要做蛋白激酶C在糖尿病方面的实验，求助各位高手有没有蛋白激酶C信号通路的图片，最好带注解，十分感谢。 石依信念 我也想要～～～～ 黑胡桃 [img]data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAskAAAGdCAYAAADgwu6RAAAgAElEQVR4Aey9B7xdxZXmu04
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