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P00206 Recombinant Human TRAN

CE/RANK L/TNFSF11/CD254 细胞因子/蛋白
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  • ¥1560 - 21120
  • Solarbio已认证
  • P00206
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥4576.0
    规格:10ug产品价格:¥1560.0
    Recombinant Human Receptor Activator of NF-kappa-B ligand is produced by our E.coli expression system and the target gene encoding Ile140-Asp317 is expressed with a 6His tag at the N-terminus.
    基本信息
    基因名
    别名CD254;ODF;OPGL;RANK L;TNFSF11;CD254;Osteoclast differentiation factor;Receptor activator of nuclear factor kappa-B ligand;tumor necrosis factor ligand superfamily member 11
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明CD254,also known as RANKL,TNFSF11,TRANCE,OPGL and ODF,is a type II membrane protein of the tumor necrosis factor (TNF) superfamily,and affects the immune system and control bone regeneration and remodeling.RANKL is the ligand of nuclear factor (NF)-κB (RANK).When RANKL binds to RANK,it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6).This results in the activation of several downstream signaling cascades,including the NFκB,mitogen-activated protein kinases (MAPK),activating protein 1 (AP-1),and nuclear factor of activated T cells (NFATc1),resulting in the formation of multinucleated bone-resorbing osteoclasts.RANKL is widely expressed in skeletal muscle,thymus,liver,colon,small intestine,adrenal gland,osteoblast,mammary gland epithelial cells,prostate and pancreas.
    来源E.coli
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
    单位

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    P00206 Recombinant Human TRANCE/RANK L/TNFSF11/CD254 细胞因子/蛋白
    ¥1560 - 21120