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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥4576.0 |
| 规格: | 10ug | 产品价格: | ¥1560.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | CD254;ODF;OPGL;RANK L;TNFSF11;CD254;Osteoclast differentiation factor;Receptor activator of nuclear factor kappa-B ligand;tumor necrosis factor ligand superfamily member 11 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | CD254,also known as RANKL,TNFSF11,TRANCE,OPGL and ODF,is a type II membrane protein of the tumor necrosis factor (TNF) superfamily,and affects the immune system and control bone regeneration and remodeling.RANKL is the ligand of nuclear factor (NF)-κB (RANK).When RANKL binds to RANK,it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6).This results in the activation of several downstream signaling cascades,including the NFκB,mitogen-activated protein kinases (MAPK),activating protein 1 (AP-1),and nuclear factor of activated T cells (NFATc1),resulting in the formation of multinucleated bone-resorbing osteoclasts.RANKL is widely expressed in skeletal muscle,thymus,liver,colon,small intestine,adrenal gland,osteoblast,mammary gland epithelial cells,prostate and pancreas. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| 单位 | 支 |
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