P00204 Recombinant Human B7-1

Recombinant Human Activation B7-1 antigen is produced by our Mammalian expression system and the target gene encoding Val35-Asn242 is expressed with a 6His tag at the C-terminus.

基本信息
基因名
别名	CD80;Activation B7-1 antigen;B7;BB1;CD28LG1;CD28LGB7-1 antigen;T-lymphocyte activation antigen CD80
外观(性状)	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度	≥95% as determined by reducing SDS-PAGE.
储存条件	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
背景说明	Cluster of Differentiation 80，also called B7-1，is a member of cell surface immunoglobulin superfamily which plays key，yet distinct roles in the activation of T cells.It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.Studies have shown that CTLA-4 binds mostly to CD80.The structure presents two extracellular domains: a membrane distal variable-like domain (IgV) and a membrane proximal Ig constant-like domain (IgC) along with an intracellular domain.Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region.CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells，macrophages and dendritic cells.
来源	Human cells
溶剂	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素	Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
单位	支