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- 2026年08月13日
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- 文献和实验
- 技术资料
- 保质期：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 保存条件：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 英文名：
IL-2
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ¥728.00 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ¥2756.00 |
| 规格： | 500ug | 产品价格： | ¥14784.00 |
| 规格： | 1mg | 产品价格： | ¥21120.00 |
| 基因名 | IL-2 |
| 别名 | aldesleukin; interleukin 2; interleukin-2; IL-2; IL2; T-cell growth facter; T cell growth factor; TCGF |
| 蛋白号 | P04351 |
| 种属 | Mouse |
| 宿主 | E.coli |
| 产品描述 | Recombinant Mouse Interleukin-2 is produced by our E.coli expression system and the target gene encoding Ala21-Gln169 is expressed. |
| 区间范围 | Ala21-Gln169 |
| 标签信息 | Tag free |
| 预测分子量 | 17.4 KDa |
| 表观分子量 | 17 KDa, reducing conditions |
| 纯度 | ≥95% by SDS‐PAGE. |
| 内毒素 | <0.1ng/ug(1EU/ug)as determined by LAL test. |
| 溶剂 | Lyophilized from a 0.2 μm filtered solution of 20mM Sodium Citrate, 0.2% Tween 80, pH 3.0. |
| 复溶 | Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 | Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: 2-8°C for 2-7 days under sterile conditions after redissolves; -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; -20°C to -70℃ for 12 months in lyophilized state. |
| 运输条件 | 冷冻运输 |
| 背景说明 | Interleukin 2 (IL-2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21.Each member of this family has a four alpha helix bundle.IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma.The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family.Mature mouse IL-2 shares 56% and 73% aa sequence identity with human and rat IL-2, respectively.IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL-2 may be a key cytokine in the natural suppression of autoimmunity. |
| 细胞活性 | Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells.The specific activity of Recombinant Mouse IL-2 is ≥1×107 IU/mg. (QC verified) |
| ELISA活性 | No activity experimental data, to be verified. |
| SPR/BLI活性 | Loaded Human IL-2RA-Fc on Protein A Biosensor, can bind Mouse IL-2 with an affinity constant of 0.17 uM as determined in BLI assay. |
| 研究领域 | 炎症与免疫调节 |
| 英文名称 | IL-2 |
| 中文名称 | IL-2蛋白 |
| 单位 | 支 |
| 规格 | 10ug ; 50ug ; 500ug ; 1mg |
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文献和实验with a Ca2+ -free medium or with trypsin/dispase. The latter facilitates the introduction of recombinant or trappable probes and microimaging studies of, for example, changes in cytosolic-free Ca2+ concentration or the dynamics of individual organelles
IL-2 Plasmid Electroporation: From Preclinical Studies to Phase I Clinical Trial
its systemic concentration, in comparison with systemic delivery of the recombinant cytokine. Nonclinical Investigational New Drug application-enabling studies were performed in mice to evaluate the effect of intratumoral administration of murine IL-2 pDNA
Purification of Recombinant Poly(ADP-Ribose) Polymerases
, more than 11 mg of pure and highly active mouse PARP-2 can be obtained from 1 L of Sf9 insect cell culture.
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