P00160 Recombinant Human FGF1

Recombinant Human Fibroblast growth factor 19 is produced by our E.coli expression system and the target gene encoding Phe27-Lys216 is expressed with a 6His tag at the N-terminus.

基本信息
基因名
别名	Fibroblast growth factor 19;FGF-19;FGF19
外观(性状)	Lyophilized from a 0.2 μm filtered solution of 20mM PB，150mM NaCl,pH7.4.
纯度	≥95% as determined by reducing SDS-PAGE.
储存条件	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
背景说明	Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family.FGF19 is expressed in fetal brain，cartilage，retina，and adult gall bladder.FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1，-2，-3，and -4，all with intrinsic tyrosine kinase activity.FGFRs can be important for regulation of glucose and lipid homeostasis.FGF19 has important roles as a hormone produced in the ileum in response to bile acid absorption.It has been shown to cause resistance to diet-induced obesity and insulin desensitization and to improve insulin，glucose，and lipid profiles in diabetic rodents.FGF19 can be considered as a regulator of energy expenditure.
来源	E.coli
溶剂	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素	Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
单位	支