P00127 Recombinant Human TGFB

Recombinant Human Transforming Growth Factor-beta Receptor Type II is produced by our Mammalian expression system and the target gene encoding Thr23-Asp159 is expressed with a Fc tag at the C-terminus.

基本信息
基因名
别名	TGF-beta receptor type-2;TGF-beta type II receptor;TGFBR2;Transforming growth factor-beta receptor type II
外观(性状)	Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2.
纯度	≥95% as determined by reducing SDS-PAGE.
储存条件	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
背景说明	TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain.TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta.Signals triggered through the TGF-beta receptor complex prompt various responses by the cell.One such response is to inhibit cell growth and division.Based on this action，the TGF-beta receptor type 2 is sometimes called a tumor suppressor.Defects in TGFBR2 have been associated with Marfan syndrome，Loeys-Deitz aortic aneurysm syndrome，Osler-Weber-Rendu syndrome and the development of various types of tumors.
来源	Human cells
溶剂	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素	Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
单位	支