P00105 Recombinant Human VEGF

Recombinant Human Vascular Endothelial Growth Factor A is produced by our Mammalian expression system and the target gene encoding Ala27-Arg147 is expressed with a 6His tag at the C-terminus.

基本信息
基因名
别名	Vascular endothelial growth factor A;VEGF-A;Vascular permeability factor;VPF;VEGFA;VEGF
外观(性状)	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度	≥95% as determined by reducing SDS-PAGE.
储存条件	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
背景说明	Human VEGF121，also known as Vascular endothelial growth factor A，VEGFA，Vascular permeability factor，VPF and VEGF，is a homodimeric，heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family.VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects，including mediating increased vascular permeability，inducing angiogenesis，vasculogenesis，permeabilization of blood vessels and endothelial cell growth，increasing microvascular permeability，promoting cell migration and inhibiting apoptosis.Alternatively spliced transcript variants of VEGF-A encod either secreted or cell-associated isoforms.The lymphangiogenesis may be promoted by upregulation of VEGF121，which may in turn act in part via induction of VEGF-C.It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors，heparan sulfate and heparin.NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145.Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways，does not activate angiogenesis and inhibits tumor growth.
来源	Human cells
溶剂	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素	Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
单位	支