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- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥14112.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥9888.0 |
| 规格： | 50ug | 产品价格： | ￥4576.0 |
| 规格： | 10ug | 产品价格： | ￥1560.0 |
Recombinant Mouse Interleukin-1 beta is produced by our E.coli expression system and the target gene encoding Val118-Ser269 is expressed.
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Ginsenoside Rh2(S) maintains cytoskeleton homeostasis and inhibits pyroptosis to resist cisplatin-induced cardiotoxicity through FGFR1/HRAS axis
成员:Hongbo Teng, Shuai Huang, Xialin Sun, Haohao Wang, Xv Wang, Wenxin Zhang, Haijing Wang, Shurong Qu, Zhengxuan Yu, Yan Zhao, Shuangli Liu
论文因子:6.7 发表期刊:PHYTOMEDICINE pmid:39879704
| 基本信息 | |
| 基因名 | |
| 别名 | Interleukin-1 Beta;IL-1 Beta;Il1b |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 50mM TrisHCl, 50mM NaCl, pH 8.0. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Interleukin-1 (IL-1) designates two proteins，IL-1α and IL-1β，which are the products of distinct genes，but recognize the same cell surface receptors.IL-1α and IL-1β are structurally related polypeptides that show approximately 25% homology at the amino acid level.Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents，infections，or microbial endotoxins.The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa.The specific protease responsible for the processing of IL-1β，designated interleukin 1β-converting enzyme (ICE)，has been described.Mature human and mouse IL-1β share approximately 75% amino acid sequence identity and human IL-1β has been found to be active on murine cell lines. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Ginsenoside Rh2(S) maintains cytoskeleton homeostasis and inhibits pyroptosis to resist cisplatin-induced cardiotoxicity through FGFR1/HRAS axis
成员:Hongbo Teng, Shuai Huang, Xialin Sun, Haohao Wang, Xv Wang, Wenxin Zhang, Haijing Wang, Shurong Qu, Zhengxuan Yu, Yan Zhao, Shuangli Liu
论文因子:6.7 发表期刊:PHYTOMEDICINE pmid:39879704
Mouse Strains and Genetic Nomenclature
Bishop, C.E., Boursot, P., Baron, B., Bonhomme, F., and Hatat, D. 1985. Most classical Mus musculus domesticus laboratory mouse strains carry a Mus musculus musculus Y chromosome. Nature 315:70‐72
Immunity：厦门大学韩家淮团队揭示 PELO 控制 NOD 样受体家族蛋白寡聚化组装和激活的机制
的炎症小体（Inflammasome），NOD2 等形成的 Nodosome，从而激活 NF-κB 通路、MAPK 通路、细胞焦亡等，释放 TNFα，IL-1β 和 IL-18 等炎性细胞因子，介导下游一系列免疫炎症级联反应【1,2】。这是机体最为基本的天然免疫防御反应之一，在机体清除病原感染和内源危险信号中发挥至关重要的作用。在人体中，多个 NLR 基因突变导致的异常激活也被发现参与了脓毒症、炎性肠病等多种重大炎性疾病的病理进程。 NLR 家族蛋白在结构上都含有一个核苷酸结合寡聚化结构域
的关系理不出头绪。GSK-3 beta 总蛋白减少，p-GSK-3 beta (ser 9)增加，是不是足以说明有活性的GSK-3 beta 减少更多，这样理解不知道对不对，希望给以指点。 galaxy22 楼主你好，请问你做出结果的tyr216的抗体是哪个公司的。。。我做出来总量是减少的，active B catenin是减少的，那我有必要做ser9 和tyr216的磷酸化形式吗？我想研究wnt和akt。。。 棉花糖的温柔
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