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- 文献和实验
- 技术资料
- 保质期：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 保存条件：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 英文名：
IL-4
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 规格：
10ug/1mg/500ug/50ug
| 规格： | 10ug | 产品价格： | ¥1217.00 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ¥16896.00 |
| 规格： | 500ug | 产品价格： | ¥11808.00 |
| 规格： | 50ug | 产品价格： | ¥3640.00 |
| 基因名 | IL-4 |
| 别名 | Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4 |
| 蛋白号 | P05112 |
| 种属 | Human |
| 宿主 | E.coli |
| 产品描述 | Recombinant Human Interleukin-4 is produced by our E.coli expression system and the target gene encoding His25-Ser153 is expressed. |
| 区间范围 | His25-Ser153 |
| 标签信息 | Tag free |
| 预测分子量 | 13-14 kDa |
| 表观分子量 | 13-14 KDa, reducing conditions |
| 纯度 | ≥95% by SDS‐PAGE. |
| 内毒素 | <0.01EU/ug as determined by LAL test. |
| 溶剂 | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.2. |
| 复溶 | Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 | Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: 2-8°C for 2-7 days under sterile conditions after redissolves; -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; -20°C to -70℃ for 12 months in lyophilized state. |
| 运输条件 | 冷冻运输 |
| 背景说明 | Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response. |
| 细胞活性 | Measured in a cell proliferation assay using TF1 human erythroleukemic cells. The ED50 for this effect is 10-70 pg/ml. |
| ELISA活性 | No activity experimental data, to be verified. |
| SPR/BLI活性 | Loaded Cynomolgus IL-4RA-Fc on Protein A Biosensor, can bind Human IL-4 with an affinity constant of <10-3 nM as determined in BLI assay. |
| 研究领域 | 炎症与免疫调节 |
| 英文名称 | IL-4 |
| 中文名称 | IL-4蛋白 |
| 单位 | 支 |
| 规格 | 500ug ; 50ug ; 10ug ; 1mg |
答：您好，需要根据细胞来源和诱导方向去参考相关文献进行选择。
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