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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder:2-8℃,2 years;Insolvent(母液):-20℃,6 months;-80℃,1 year
- 保质期:
Powder:2-8℃,2 years;Insolvent(母液):-20℃,6 months;-80℃,1 year
- 英文名:
BAY-179
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
5mg
| 基本信息 | |
| CAS | |
| 英文名称 | BAY-179 |
| 分子式 | C23H21N5OS |
| 分子量 | 415.51 |
| 溶解性 | Soluble in DMSO |
| 纯度 | ≥98% |
| 外观(性状) | Solid |
| 储存条件 | Powder:2-8℃,2 years;Insolvent(母液):-20℃,6 months;-80℃,1 year |
| 靶点 | mitochondrial complex I |
| 通路 | Others |
| 背景说明 | BAY-179是mitochondrial complex I的抑制剂。 |
| 生物活性 | BAY-179 is an inhibitor of mitochondrial complex I, also known as NADH dehydrogenase (IC50s = 79, 38, 27, and 47 nM for the human, mouse, rat, and dog enzymes, respectively).1 See the Structural Genomics Consortium (SGC) website for more information.[1] |
| 数据来源文献 | [1]. Mowat J, Ehrmann AHM, Christian S, Sperl C, Menz S, Günther J, Hillig RC, Bauser M, Schwede W. Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179. ACS Med Chem Lett. 2022 Feb 18;13(3):348-357. |
| 单位 | 瓶 |
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文献和实验|998894|gb|S78179.1|S78179 Oryctolagus cuniculus type XII... 32 0.037 gi|31072033|gb|AC122153.4| Oryctolagus cuniculus clone LB1-... 28 0.58 gi|1496|emb|X52496.1|OCCAATP Rabbit mRNA for calcium ATPase 28 0.58 gi|1468|emb|X02814.1|OCATPDR Rabbit mRNA
bSuKm1foWOq5wNpboNQLmlo2Fn6wS/ZjqQvb2Gy88CULhuQ5TVEaoQ2gtdU9TtPRtFgh/BbLYDrlNQtO4GHJJVoXvFg0UhwMJHFBz8InEEZPh1ZysOf82LTuunw2ReE8zcuwcvBs9FhSwx9ygL9MIXF3cE5dCHQW6tUCFBRmfdHz/iB3LBwEAHsR9N0y8571/wU9NGdk3x4RpaZL/f4OLeO2i7bi76ls+Z7gQPsYry5csjR44c9GX7BuIIRl9f
of complex and protein alone with the naked eye or a light microscope, crystals of covalently Cy5?labeled DNA can be directly used for X?ray diffraction data collection. Curr. Protoc. Nucleic Acid Chem. 46:7.15.1?7.15.8. © 2011 by John Wiley & Sons
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