IX0180 XTT钠盐 反应底物/理化检测 索莱宝

In Vitro

Cell（C. albicans CAI4-TDH3-GFP cells）

Each well was photographed under an Olympus fluorescence microscope. Meanwhile, biofilm formation was quantitatively analyzed using the XTT (Solarbio, catalog no. IX0180) reduction assay.

来源文献：Wang X, Jin X, Zhao F, Xu Z, Tan W, Zhang J, Xu Y, Luan X, Fang M, Xie Z, Chang W, Lou H. Structure-Based Optimization of Novel Sterol 24-C-Methyltransferase Inhibitors for the Treatment of Candida albicans Infections. J Med Chem. 2024 Jun 13;67(11):9318-9341. doi: 10.1021/acs.jmedchem.4c00470. Epub 2024 May 19. PMID: 38764175.

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标题:Inhibitory effect and possible mechanism of phenyllactic acid on Aspergillus flavus spore germination

成员:Minghua Li, Binbin Yao, Xiumei Meng

论文因子:2.65 发表期刊:JOURNAL OF BASIC MICROBIOLOGY pmid:35925551

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标题:Inhibition efficiency of 304-Cu stainless steel against oral bacterial biofilm

成员:Yiliang Lan, Jie Yang, Xianbo Liu, Hanyu Zhao, Xinrui Zhang, Xueliang Yin, Chunguang Yang, Ke Yang, Yi Liu

论文因子:2.744 发表期刊:Journal of Applied Biomaterials & Functional Materials pmid:35086381

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标题:A novel visible light-curing chitosan-based hydrogel membrane for guided tissue regeneration

成员:Xiaojie Xing, JingJing Su, Yuan Liu, Honglei Lin, Yinghui Wang, Hui Cheng

论文因子:5.999 发表期刊:COLLOIDS AND SURFACES B-BIOINTERFACES pmid:35961119

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标题:Structure-Based Optimization of Novel Sterol 24-C-Methyltransferase Inhibitors for the Treatment of Candida albicans Infections

成员:Xue Wang, Xueyang Jin, Fabao Zhao, Zejun Xu, Wenzhuo Tan, Jiaozhen Zhang, Yuliang Xu, Xiaoyi Luan, Min Fang, Zhiyu Xie, Wenqiang Chang, Hongxiang Lou

论文因子:7.3 发表期刊:JOURNAL OF MEDICINAL CHEMISTRY pmid:38764175

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标题:Extraction of Extracellular Matrix in Static and Dynamic Candida Biofilms Using Cation Exchange Resin and Untargeted Analysis of Matrix Metabolites by Ultra-High-Performance Liquid Chromatography-Tandem Quadrupole Time-of-Flight Mass Spectrometry (UPLC-Q-

成员:Da W; Shao J; Li Q; Shi G; Wang T; Wu D; Wang C

论文因子:5.2 发表期刊:Front Microbiol pmid:31110494

基本信息
CAS	No.111072-31-2
中文名称	XTT钠盐
英文名称	XTT Sodium Salt
别名	;XTT钠盐;3，3-[1-(苯氨酰基)-3，4-四氮唑]-二(4-甲氧基-6-硝基)苯磺酸钠
分子式	C22H16N7NaO13S2
分子量	673.52
溶解性	Soluble in Water ≥10mg/mL(Need ultrasonic or Water bath)(该产品在溶液状态不稳定，建议您现用现配)
纯度	≥90%
外观(性状)	Light yellow to yellow Solid
储存条件	Powder: 2-8℃，2 years
EC	EINECS 601-039-1
MDL	MFCD00083517
SMILES	COC1=CC(=C(C=C1N2N=C(N=[N+]2C3=CC(=C(C=C3OC)[N+](=O)[O-])S(=O)(=O)[O-])C(=O)NC4=CC=CC=C4)S(=O)(=O)[O-])[N+](=O)[O-].[Na+]
InChIKey	JACYMBNQPPWQML-UHFFFAOYSA-M
InChI	InChI=1S/C22H17N7O13S2.Na/c1-41-17-8-15(28(31)32)19(43(35,36)37)10-13(17)26-24-21(22(30)23-12-6-4-3-5-7-12)25-27(26)14-11-20(44(38,39)40)16(29(33)34)9-18(14)42-2;/h3-11H,1-2H3,(H2-,23,30,35,36,37,38,39,40);/q;+1/p-1
PubChem CID	14195569
靶点	Others
通路	Others
背景说明	是一种四唑盐,在生物还原时可生成水溶性甲臜产物。常用于评估指示氧化还原电位的细胞活力。
单位	瓶