- ￥650 - 2500
- 合肥善本生物
- 62346
- 2025年07月23日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
详询
- 库存：
50
- 供应商：
广州市左克生物
- 规格：
20 μL/50 μL/100 μL
| 规格： | 20 μL | 产品价格： | ￥650.0 |
|---|---|---|---|
| 规格： | 50 μL | 产品价格： | ￥1350.0 |
| 规格： | 100 μL | 产品价格： | ￥2500.0 |
货号：62346
名称：KD-Validated Anti-Methyl-CpG Binding Domain Protein 1 Rabbit mAb（KD KO验证抗体，高特异性）
Applications Tested：WB, FCM
Species Reactivity：H, R
Clone ID：24GB405
UniProt Entry：Q9UIS9
NCBI Gene Entry：4152
Aliases：Methyl-CpG Binding Domain Protein 1; CXXC3; PCM1; Protein Containing Methyl-CpG-Binding Domain 1; Methyl-CpG-Binding Domain Protein 1; CXXC-Type Zinc Finger Protein 3; Protein Containing MBD 1; The Regulator Of Fibroblast Growth Factor 2 (FGF-2) Transcription; Methyl-CpG-Binding Protein MBD1; RFT
Research Field：Epigenetics and Nuclear Signaling
公司介绍：
GenuIN合肥善本生物现有高标准研发生产基地面积3018平方米，通过专有的ShGE™基因沉默(Gene Silencing, 又叫Gene Knockdown, KD)平台筛选抗体并以此形成经过验证的三大资源库即慢病毒库、稳转细胞系库和细胞裂解物库，建立产业链上、下游的通用抗体标准语言，提供基因沉默整体解决方案，提升国产生物制剂的国际竞争力，帮助科研人员获得出色的研究成果。 主要产品有经过KD验证的高特异性抗体、慢病毒、稳转细胞裂解物，以及配套试剂。
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文献和实验Enrichment of Methylated DNA by Methyl-CpG Immunoprecipitation
to methylated DNA. Methyl-CpG Immunoprecipitation (MCIp) employs an immobilized recombinant human methyl-CpG binding domain protein 2, MBD2, which binds methylated CpGs in double-stranded DNA. Elution with increasing salt concentrations allows the fractionated
of methyl′CpG binding proteins was described 7 . The five members of this family share a similar methyl′CpG binding domain. One of these proteins, MeCP2, is known to be necessary for embryonic development, although the effects on imprinted genes
of mutations in the BCR-ABL1 kinase domain (KD) that abrogate binding of imatinib. Although KD mutations are quite heterogeneous, the identification of the exact mutation site is clinically important, as some mutations, but not others, can be effectively
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