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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
详询
- 库存:
50
- 供应商:
广州市左克生物
- 规格:
20 μL/50 μL/100 μL
| 规格: | 20 μL | 产品价格: | ¥650.0 |
|---|---|---|---|
| 规格: | 50 μL | 产品价格: | ¥1350.0 |
| 规格: | 100 μL | 产品价格: | ¥2500.0 |
货号:63283
名称:KD-Validated Anti-G Protein-Coupled Receptor Kinase 6 Rabbit mAb(KD KO验证抗体,高特异性)
Applications Tested:WB, FCM
Species Reactivity:H, M, R
Clone ID:24GB4870
UniProt Entry:P43250
NCBI Gene Entry:2870
Aliases:GRK6; G Protein-Coupled Receptor Kinase 6; GPRK6; EC 2.7.11.16; G Protein-Coupled Receptor Kinase GRK6; EC 2.7.11
Research Field:Signal Transduction; Cardiovascular
公司介绍:
GenuIN合肥善本生物现有高标准研发生产基地面积2860平方米,通过专有的ShGE™基因沉默(Gene Silencing, 又叫Gene Knockdown, KD)平台筛选抗体并以此形成经过验证的三大资源库即慢病毒库、稳转细胞系库和细胞裂解物库,建立产业链上、下游的通用抗体标准语言,提供基因沉默整体解决方案,提升国产生物制剂的国际竞争力,帮助科研人员获得出色的研究成果。 主要产品有经过KD验证的高特异性抗体、慢病毒、稳转细胞裂解物,以及配套试剂。
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文献和实验Assay of G Protein-Coupled Receptor Kinase Activity by Rhodopsin Phosphorylation
Agonist occupation of G protein-coupled receptors (GPCRs) leads to a cellular response that wanes, or desensitizes, with prolonged agonist exposure. Different cellular mechanisms contribute to desensitization, including the altered function
Elucidating Agonist-Selective Mechanisms of G Protein-Coupled Receptor Desensitization
(PKC) and G protein-coupled receptor kinase/arrestin respectively. This could explain why opioid agonists have variable clinical profiles and liabilities to induce tolerance and dependence. Here we describe the experimental approaches
Activation of MAPKs by G Protein-Coupled Receptors
G protein-coupled receptors (GPCRs) constitute the largest family of cell-surface molecules involved in signal transmission. These receptors play key physiologic roles, with their dysfunction resulting in a number of disease states
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