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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Human
- 亚型:
IgG1, kappa
- 形态:
Liquid
- 保存条件:
0.01M PBS pH 7.4
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
1 year
- 抗原来源:
Human
- 目录编号:
HA962016
- 级别:
科研级别
- 库存:
999
- 供应商:
abinScience
- 宿主:
Human
- 应用范围:
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- 浓度:
1mg/mL
- 靶点:
Metalloreductase STEAP2, EC:1.16.1.-, Prostate cancer-associated protein 1, Protein up-regulated in metastatic prostate cancer, PUMPCn, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1, STEAP2
- 抗体英文名:
Research Grade Anti-Human STEAP2 Antibody (AZD0516)
- 抗体名:
Research Grade Anti-Human STEAP2 Antibody (AZD0516)
- 规格:
100ul

| Product name | Research Grade Anti-Human STEAP2 Antibody (AZD0516) |
|---|---|
| Catalog No. | HA962016 |
| Host species | Human |
| Species reactivity | Human |
| Immunogen | / |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 |
| Purity | >95% as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Isotype | IgG1, kappa |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | Metalloreductase STEAP2, EC:1.16.1.-, Prostate cancer-associated protein 1, Protein up-regulated in metastatic prostate cancer, PUMPCn, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1, STEAP2 |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin level | < 1EU/mg |
| Expression system | / |
| Accession | Q8NFT2 |
| Alternative Names | / |
| Clone ID | AZD0516 |
| Species | / |
| Product Usage Information | / |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003, abinScience has inherited advanced technologies and high-quality standards. In particular, the XtenCHO™ system developed by ProteoGenix, which has two modes of transient expression and stable expression, has been widely recognized as a core technology to improve the efficiency of protein production, providing a solid foundation for abinScience's product research and development.
Product categories and application fields.
Main products.
10000+ high-activity proteins.
15000+ antibody series products:
Classic monoclonal antibody.
Monoclonal antibody
Internal control antibody, labeled antibody.
High-quality phosphorylation antibodies.
Highly specific nanobodies and small molecule antibodies.
Functional antibodies in vivo.
Low-background flow cytometry antibodies.
DNA/RNA antibodies and PEG antibodies.
1000+ reagent kit series products.
Large-scale packaging customization services: We offer personalized antibody design, protein production, molecular optimization, and experimental development services.
Application field
Infectious disease research: including viruses, superbugs, parasites, etc.
Neuroscience research: Supporting research on neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
Immunology research: Covers the research needs of immune activation, inhibition, and allergies and abnormal reactions.
Oncology research: Supporting the development of tumor biology and anti-tumor drugs.
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文献和实验• STEAP2 promotes hepatocellular carcinoma progression via increased copper levels and stress-activated MAP kinase activity., PMID:38830975
• STEAP2 Knockdown Reduces the Invasive Potential of Prostate Cancer Cells., PMID:29674723
• A role for STEAP2 in prostate cancer progression., PMID:25248617
• Six-transmembrane epithelial antigen of the prostate (STEAP1 and STEAP2)-differentially expressed by murine and human mesenchymal stem cells., PMID:19196137
• STEAP2 promotes osteosarcoma progression by inducing epithelial-mesenchymal transition via the PI3K/AKT/mTOR signaling pathway and is regulated by EFEMP2., PMID:36316642
• METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition., PMID:35436987
• STEAP1 protein overexpression is an independent marker for biochemical recurrence in prostate carcinoma., PMID:24025158
• STEAP2 is down-regulated in breast cancer tissue and suppresses PI3K/AKT signaling and breast cancer cell invasion in vitro and in vivo., PMID:31696760
• STAMPing at the crossroads of normal physiology and disease states., PMID:26911931
Cryopreservation of Human Hepatocytes for Clinical Use
for cell transplantation at the Cell Isolation Unit at King’s College Hospital, London, are described. All procedures must be performed in a clean GMP environment using materials and reagents which are of pharmaceutical grade. The cryopreservation media
7.5. Prepare the working dilution of the primary antibody in 1.0% crystalline-grade Bovine Serum Album (BSA) in 1x PBS. Use BrdU antibody (Dako Catalog No. M744) at 1:20 dilution. Blot off PBS and apply 150µl of working dilution. Incubate sections
after 2 min. Apply primary antibody when pH is 7.0-7.5. Prepare the working dilution of the primary antibody in 1.0% crystalline-grade Bovine Serum Album (BSA) in 1x PBS. Use BrdU antibody (Dako Catalog No. M744) at 1:20 dilution. Blot off PBS and apply
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