- ￥1668
- abinScience
- China
- HB342014
- 2026年03月03日
- ELISA, IHC, WB
- Rabbit
- Human, Mouse, Frog
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Rabbit
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse, Frog
- 保质期：
1 year
- 抗原来源：
Rabbit
- 目录编号：
HB342014
- 级别：
科研级别
- 库存：
999
- 供应商：
abinScience
- 宿主：
Rabbit
- 应用范围：
ELISA, IHC, WB
- 浓度：
1mg/mL
- 靶点：
Transcription factor SOX-4; SOX4
- 抗体英文名：
Anti-SOX4 Polyclonal Antibody
- 抗体名：
Anti-SOX4 Polyclonal Antibody
- 规格：
100ul
| Product name | Anti-SOX4 Polyclonal Antibody |
|---|---|
| Catalog No. | HB342014 |
| Host species | Rabbit |
| Species reactivity | Human, Mouse, Frog |
| Immunogen | E. coli - derived recombinant human SOX4 (Met1-Tyr128). |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Purity | / |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | ELISA, IHC, WB |
| Target | Transcription factor SOX-4; SOX4 |
| Purification | Purified by antigen affinity column. |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | / |
| Accession | Q06945, Q06831, Q91731, P40650, Q62249, O15370, Q04890 |
| Alternative Names | / |
| Clone ID | / |
| Species | / |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003, abinScience has inherited advanced technologies and high-quality standards. In particular, the XtenCHO™ system developed by ProteoGenix, which has two modes of transient expression and stable expression, has been widely recognized as a core technology to improve the efficiency of protein production, providing a solid foundation for abinScience's product research and development.
Product categories and application fields.
Main products.
10000+ high-activity proteins.
15000+ antibody series products:
Classic monoclonal antibody.
Monoclonal antibody
Internal control antibody, labeled antibody.
High-quality phosphorylation antibodies.
Highly specific nanobodies and small molecule antibodies.
Functional antibodies in vivo.
Low-background flow cytometry antibodies.
DNA/RNA antibodies and PEG antibodies.
1000+ reagent kit series products.
Large-scale packaging customization services: We offer personalized antibody design, protein production, molecular optimization, and experimental development services.
Application field
Infectious disease research: including viruses, superbugs, parasites, etc.
Neuroscience research: Supporting research on neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
Immunology research: Covers the research needs of immune activation, inhibition, and allergies and abnormal reactions.
Oncology research: Supporting the development of tumor biology and anti-tumor drugs.
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文献和实验• Oct4A palmitoylation modulates tumorigenicity and stemness in human glioblastoma cells., PMID:35727735
• METTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer., PMID:32552762
• Pharmacological blockade of TEAD-YAP reveals its therapeutic limitation in cancer cells., PMID:36347861
• SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysis., PMID:36585108
• Sox4 B-lymphocyte progenitors., PMID:24970928
• SOX4: The unappreciated oncogene., PMID:31445218
• SOX11 in EBV-negative Burkitt lymphoma., PMID:38990541
• Pleiotropic function of SRY-related HMG box transcription factor 4 in regulation of tumorigenesis., PMID:23080209
• The author replies., PMID:30243318
Cancer Cell：整合素 αvβ6-TGFβ-SOX4 途径驱动三阴性乳腺癌的免疫逃逸
近几年，肿瘤免疫治疗研究不断升温，特别是抗 PD-1 抗体治疗在霍奇金淋巴瘤、肝癌、非小细胞肺癌和食管鳞癌等癌症中表现出卓越的疗效。但是肿瘤免疫治疗对许多起源于上皮组织的实体瘤疗效有限，包括三阴性乳腺癌。三阴性乳腺癌（TNBC）有很高的转移扩散倾向。虽然近期抗 PD-L1 抗体联合紫杉醇在治疗转移性 TNBC 上表现出不错的效果，但仍然有大量的患者未能从免疫治疗中获益。因此，解析 TNBC 肿瘤免疫逃逸机制显得尤为重要！2020 年 12 月 31 日，哈佛医学院的 Kai W
Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
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