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文献和实验Detection of APP Intracellular Domain in Brain Tissue
The cleavage of amyloid precursor protein (APP) by γ-secretase produces Aβ peptides, which are prominent features in Alzheimer’s disease and have been extensively studied. By contrast, APP intracellular domain (AICD), also a product
Intracellular Antibody Capture (IAC) Methods for Single Domain Antibodies
Intracellular single domain antibodies are recombinant proteins, comprising one variable region domain fragment, that bind specifically to intracellular molecules and can interfere with their particular functions within various cellular
Construction of a Human Antibody Domain (VH) Library
human CDRs and synthetic CDRs are combined into a single-domain (VH) framework.
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