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- 文献和实验
- 技术资料
- 供应商:
广州威佳科技有限公司
- CAS号:
5614-64-2
- 规格:
5mg
8-Hydroxyguanine是由活性氧物质产生的主要诱变前损伤。 它导致G-T和A-C置换。
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文献和实验相关实验
Detection of Aldehydic DNA Lesions Using Aldehyde Reactive Probe
damage (2 ,3 ). Although the heterocyclic bases of nucleic acids are important sites of free radical-mediated alteration, such as 8-hydroxyguanine (8-OHG) (4 ), the sugar-phosphate backbone is also highly vulnerable to attack. Abstraction of a hydrogen
chromatography with electrochemical detection or with salicylate treatment (5 –11 ), and immunohistochemistry (12 –17 ). Recently, a nucleic acid probe has been generated that binds to an abnormal guanine base, 8-hydroxyguanine (oh8G) (Fig. 1 ) (18
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8-Hydroxyguanine
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