- ￥2800 - 4550
- Solarbio
- K009936P
- 北京
- 2025年07月20日
- WB IHC
- Rabbit
- Human Mouse Rat
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 靶点：
Phospho-AKT1-S473
- 应用范围：
WB IHC
- 宿主：
Rabbit
- 适应物种：
Human Mouse Rat
- 供应商：
北京索莱宝科技有限公司
- 克隆性：
Polyclonal Antibody
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 形态：
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
- 亚型：
IgG
- 免疫原：
A phospho specific peptide corresponding to residues surrounding S473 of human AKT1
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥2800.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥4550.0 |
产品简介
| 单位 | 支 |
| 靶标 | Phospho-AKT1-S473 |
| 别名 | AKT;CWS6;PKB;PKB-ALPHA;PRKBA;RAC;RAC-ALPHA;AKT1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| Gene ID | 207 |
| Swiss Prot | P31749 |
| 蛋白分子量 | 48/55kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| 亚细胞定位 | Cell membrane Cytoplasm Nucleus |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding S473 of human AKT1 |
| 纯化方法 | Affinity purification |
| 背景资料 | The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. |
| 克隆类型 | Polyclonal Antibody |
备注： 
实验图 
Western blot analysis with Phospho-AKT1-S473 antibody diluted at 1:1000;Lane:Jurkat
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
Construction of Polyclonal Antibody Libraries Using Phage Display
Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified
技术资料暂无技术资料 索取技术资料
