Fenhexamid

一种杀菌剂；抑制几种B.cinerea菌株的芽管伸长和菌丝生长（EC50s分别为0.13-8.3和0.03-16.5µM）；抑制3-酮还原酶（B.cinerea酶的IC50=3µM）；ERα激动剂（酵母报告试验中的EC50=9µM）；抑制MDA-kb2细胞中双氢睾酮的雄激素作用（IC20=2.02µM）；在10µM时增加BG1细胞的增殖和迁移；在842gAI/ha时，对由S.minor和S.sclerotiorum引起的莴苣落叶病防治率分别为27.3%和13.9%。A fungicide; inhibits germ-tube elongation and mycelial growth of several strains of B. cinerea (EC50s = 0.13-8.3 and 0.03-16.5 µM, respectively); inhibits 3-ketoreductase (IC50 = 3 µM for the B. cinerea enzyme); an ERα agonist (EC50 = 9 µM in a yeast reporter assay); inhibits the androgenic effect of dihydrotestosterone in MDA-kb2 cells (IC20 = 2.02 µM); increases the proliferation and migration of BG1 cells at 10 µM; provides 27.3 and 13.9% disease control for lettuce drop caused by S. minor and S. sclerotiorum, respectively, at 842 g AI/ha.分子式C14H17Cl2NO2分子量302.2O=C(C1(CCCCC1)C)NC2=C(Cl)C(Cl)=C(C=C2)O