Thimerosal

一种汞基抗菌剂；对溶血性链球菌有抑菌作用，对荚膜梭菌、皮炎芽孢杆菌和申克沙门氏菌有抑制作用；浓度为1-250µM时，可诱导HCN-1A人类皮质神经元和各种神经母细胞瘤细胞凋亡；腹腔注射80mg/kg时，可诱导小鼠拟过敏反应模型的脚垫肿胀和背部皮肤接触性皮炎。A mercurial antimicrobial agent; bacteriostatic against hemolytic streptococci and fungistatic against H. capsulatum, B. dermatitidis, and S. schenckii; induces apoptosis in HCN-1A human cortical neurons and various neuroblastoma cells from 1-250 µM; induces footpad swelling and dorsal skin contact dermatitis in a mouse model of pseudo-allergic reaction at 80 mg/kg, i.p.分子式C9H9HgO2S • Na分子量404.8O=C([O-])C1=CC=CC=C1[S][Hg]CC.[Na+]