ARHGEF11 多克隆抗体

Western Blot（WB）已验证样本:Mouse brain

WB 1:500-1:2000

Polyclonal

IgG

Synthetic peptide of human ARHGEF11

ARHGEF11

ARHGB;ARHGEF 11;ARHGEF11;DKFZp667F1223;Glutamate transporter EAAT4 associated protein 48;GTRAP 48;GTRAP48;KIAA0380;OTTHUMP00000038716;OTTHUMP00000038717;PDZ RHOGEF;PDZ-RhoGEF;Rho guanine exchange factor (GEF) 11;Rho guanine nucleotide exchange factor (GEF) 11;Rho guanine nucleotide exchange factor 11;RhoA specific guanine nucleotide exchange factor;RhoGEF glutamate transport modulator抗体

O15085

168kDa

Cytoplasm. Membrane. Translocated to the membrane upon stimulation.

0.8 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Signal Transduction

Unconjugated

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.