NFATC2 多克隆抗体

Western Blot（WB）已验证样本:Human brain

WB 1:200-1:1000

Polyclonal

IgG

Synthetic peptide of human NFATC2

NFATC2

AI607462;cytoplasmic 2;KIAA0611;NF ATc2;NF ATp;NF-ATc2;NF-ATp;NFAC2;NFAT 1;NFAT pre existing subunit;NFAT pre-existing subunit;NFAT transcription complex;preexisting component;NFAT1;NFAT1-D;NFATc2;NFATp;Nuclear factor of activated T cells cytoplasmic 2;Nuclear factor of activated T cells cytoplasmic calcineurin dependent 2;Nuclear factor of activated T cells pre-existing component;Nuclear factor of activated T cells;preexisting component;Nuclear factor of activated T-cells;Preexisting nuclear factor of activated T cells 2;T cell transcription factor NFAT 1;T-cell transcription factor NFAT1抗体

Q13469

98kDa

Cytoplasm. Nucleus. Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The sub细胞定位 of NFATC plays a key role in the regulation of gene transcription.

0.7 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Immunology; Signal Transduction

Unconjugated

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.