Piericidin B

具有杀虫和抗菌活性的细菌代谢物；抑制分离的牛心脏线粒体中的NADH氧化酶活性；抑制分离的大鼠肝线粒体和分离的蟑螂肌肉线粒体的呼吸作用；局部应用4µg可导致87.5%的家蝇死亡；当以60、4.8和96µg/幼虫的浓度施用时，分别可导致水稻螟虫、蚕和绿毛虫幼虫死亡率达到93.3%、100%和100%；可对抗各种真菌（MIC=2-20µg/ml）以及细菌M.luteus和P.vulgaris（MIC分别为50和100µg/ml）。A bacterial metabolite with insecticidal and antimicrobial activities; inhibits NADH oxidase activity in isolated bovine heart mitochondria; inhibits respiration in isolated rat liver mitochondria and isolated cockroach muscle mitochondria; induces mortality in 87.5% of houseflies at 4 µg applied topically; induces 93.3, 100, and 100% mortality in rice stem borer, silkworm, and green caterpillar larvae, respectively, when applied at respective concentrations of 60, 4.8, and 96 µg/larva; active against various fungi (MICs = 2-20 µg/ml), as well as the bacteria M. luteus and P. vulgaris (MICs = 50 and 100 µg/ml, respectively).分子式C26H39NO4分子量429.6COC1=C(O)C(C)=C(C/C=C(C)/C/C=C/C(C)=C/[C@H]([C@@H](OC)/C(C)=C/C)C)N=C1OC