S-methyl-L-Cysteine

具有多种生物活性的半胱氨酸衍生物；MSRA的底物；在帕金森病果蝇模型的反应性攀爬试验中，可减少人类α-突触核蛋白过度表达引起的运动障碍；在丙硫氧嘧啶诱发的胆固醇代谢失调大鼠中，可防止外源性胆固醇引起的血清和肝脏总胆固醇水平升高；在以100mg/kg剂量喂食高果糖饮食的大鼠中，可降低血浆葡萄糖、胰岛素、MDA和TNF-α水平，并增加GSH水平；在二乙基亚硝胺诱发的肝癌大鼠模型中，可减少含有GST-P的肝细胞灶的数量和面积（100mg/kg，口服）。A derivative of cysteine with diverse biological activities; substrate for MSRA; decreases locomotor deficits induced by overexpression of human α-synuclein in a reactive climbing assay in a Drosophila model of Parkinson's disease; prevents exogenous cholesterol-induced increases in total cholesterol levels in serum and liver in rats with propythiouracil-induced dysregulated cholesterol metabolism; decreases plasma glucose, insulin, MDA, and TNF-α levels as well as increases GSH levels in rats fed a high-fructose diet at 100 mg/kg; reduces the number and area of hepatocellular foci containing GST-P in a rat model of diethylnitrosamine-induced hepatocarcinogenesis (100 mg/kg, p.o.).分子式C4H9NO2S分子量135.2CSC[C@H](N)C(O)=O