Methyl 3-Fluoro-4-(methylsulfo

Synthesis of (2S, 4S, 5S)-5-(t-Butoxycarbonylamino)-4-(t-Butyldimethylsilyloxy)-2-Isopropyl-7-Methyl Octanoic Acid

In an effort to produce renm mhibttory peptides, the preparation of (2 S ,4 S ,5 S )-5-( t -Butoxycarbonylamino)-4-( t -butyldimethylsilyloxy)-2-isopropyl-7-methyl octanotc acid, 15 , was carried out ( 1 ). This pseudo-dipeptide was used

Confocal Laser Scanning Microscopy Morphology and Apoptosis in Organogenesis-Stage Mouse Embryos

). We have combined fixation and clearing methods with fluorochrome staining for several purposes. In this chapter we present two methods; first, clearing with methyl salicylate (oil of wintergreen) and staining with Nile blue sulfate (NBS) (not used as a vital dye

Treating Respiratory Viral Diseases with Chemically Modified, Second Generation Intranasal siRNAs

) that were chemically modified and screened for improved stability, activity and pharmacokinetics. 2′-O -methyl (2′-O -Me) and 2′-deoxy-2′-fluoro (2′-F) substitutions in the ribose ring were incorporated in different positions of the sense and antisense strands