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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
2-8℃
- 保质期:
见包装
- 英文名:
Silibinin
- 库存:
大量现货
- 供应商:
上海研谨生物
- CAS号:
22888-70-6
- 规格:
20mg
水飞蓟宾
分析标准品,HPLC≥98%
Silibinin
CAS号:22888-70-6
分子式:C25H22O10
分子量:482.443
MDL:MFCD03225424
别名:益肝灵;西利马林;2,3-二氢-3-(4-羟基-3-甲氧*基苯基)-2-羟甲基-6-(3,5,7-三羟基-4-氧代苯并吡喃-2-基)苯并二氧六环
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货号 |
规格/参数/品牌 |
价格 |
货期 |
|
YJ-B21185-20mg |
分析标准品,HPLC≥98% |
¥180.00 |
现货 |
|
YJ-B21185-100mg |
分析标准品,HPLC≥98% |
¥480.00 |
现货 |
|
JS24053-1g |
AR,98% |
¥440.00 |
现货 |
|
JS24053-5g |
AR,98% |
¥930.00 |
现货 |
|
JS24053-25g |
AR,98% |
¥2300.00 |
现货 |
|
JS24053-100g |
AR,98% |
¥4600.00 |
现货 |
|
A10204-20mg |
分析标准品,含量97.8%,可溯源 |
¥330.00 |
现货 |
|
JY53945-1g |
98%(HPLC) |
¥180.00 |
现货 |
|
JY53945-5g |
98%(HPLC) |
¥490.00 |
现货 |
|
JY53945-25g |
98%(HPLC) |
¥1690.00 |
现货 |
产品介绍
Silibinin (Silibinin A) 为抗癌和化疗预防化合物,能抑制细胞增殖和迁移。
熔点:164-174℃
沸点:793℃ at 760mmHg
比旋光度:+8 ~ +12 ° (c=0.21in acet*one at 20 ℃)
外观:类白色结晶性粉末
溶解性:DMSO:250mg/mL(518.20mM;Needultrasonic)
储存条件:2-8℃
注意:部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。
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文献和实验参考文献(22篇)
22. [IF=7.2] Mengyao Wu et al."Multi-omics analysis reveals the anti-obesity and hepatoprotective properties in Termitomyces intermedius extracts."Journal of Future Foods.2025 Jul;:
21. [IF=4.9] Zhiwen Zhang et al."Effect of Particle Size on Physical Properties, Dissolution, In Vitro Antioxidant Activity, and In Vivo Hepatoprotective Properties of Tetrastigma hemsleyanum Diels et Gilg Powders."Pharmaceutics.2024 Nov;16(11):1352
20. [IF=5] Wei Wang et al."Beneficial effects of silibinin on serum lipids, bile acids, and gut microbiota in methionine-choline-deficient diet-induced mice."Frontiers in Nutrition.2023; 10: 1257158
19. [IF=5.9] Xiaomei Zheng et al."Eriodictyol Alleviated LPS/D-GalN-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Cell Apoptosis via PI3K/AKT Signaling Pathway."Nutrients.2023 Jan;15(20):4349
18. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747
17. [IF=3.246] Xu Renjie et al."Fabrication of Stable Apigenin Nanosuspension with PEG 400 as Antisolvent for Enhancing the Solubility and Bioavailability."Aaps Pharmscitech. 2022 Jan;23(1):1-11
16. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950
15. [IF=4.268] Jie Chen et al."Synergistic anti-inflammatory effects of silibinin and thymol combination on LPS-induced RAW264.7 cells by inhibition of NF-κB and MAPK activation."Phytomedicine. 2020 Nov;78:153309
14. [IF=11.878] Li Xinming et al."A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage."Nat Commun. 2019 Jun;10(1):1-12
13. [IF=1.908] Yan Chen et al."Characterization of glutathione conjugates derived from reactive metabolites of seven silymarin isomers."Xenobiotica. 2019;49(11):1269-1278
12. [IF=2.977] Yan-Jiao Li et al."Silibinin exerts antidepressant effects by improving neurogenesis through BDNF/TrkB pathway."Behav Brain Res. 2018 Aug;348:184
11. [IF=4.5] Wang Min et al."Silibinin Prevents Autophagic Cell Death upon Oxidative Stress in Cortical Neurons and Cerebral Ischemia-Reperfusion Injury."Mol Neurobiol. 2016 Mar;53(2):932-943
10. Li, Fang, et al. "Lactobacillus fermentum HFY06 reduced CCl 4-induced hepatic damage in Kunming mice." RSC Advances 10.1 (2020): 1-9.https:##doi.org/10.1039/C9RA08789C
9. Jie Chen, Dong-Li Li, Ling-Na Xie, Yu-ran Ma, Pan-Pan Wu, Chen Li, Wen-Feng Liu, Kun Zhang, Ren-Ping Zhou, Xue-Tao Xu, Xi Zheng, Xia Liu, Synergistic anti-inflammatory effects of silibinin and thymol combination on LPS-induced RAW264.7 cells by inhibition
8. 秦帅,吴丽丽,秦灵灵,张程斐,吴呦呦,孙伯菊,刘铜华.水飞蓟宾对C2C12细胞胰岛素抵抗的影响及机制研究[J].世界科学技术-中医药现代化,2020,22(10):3450-3455.
7. 张丽芳, 林霞, 冯星海,等. 超声辅助有机溶剂回流提取水飞蓟籽中水飞蓟素工艺的优化[J]. 中成药, 2019, 41(001):185-188.
6. 郑成凤 潘裕添 苑小宁 等. HPLC-UV-MS法对洋蓟中多酚类化合物的分析和鉴定[J]. 漳州师范学院学报(自然科学版) 2013(3):81-87.
5. 仲金秋, 曹玉珠, 徐宏江,等. 甘草酸二铵改善ConA致小鼠肝损伤的作用研究[J]. 天然产物研究与开发, 2018, 30(12):60-68.
4. 张会芳, 杨亚琛, 张久亮,等. 油菜蜂花粉加工副产物多酚对小鼠急性肝损伤的保护作用[J]. 食品安全质量检测学报, 2018, v.9(09):59-66.
3. 王立, 薛冰, 刘华石,等. 水飞蓟宾葡甲*胺渗透泵片的制备及其释放机制考察[J]. 中国医药工业杂志, 2018.
2. 王立, 杨硕, 马维阳,等. 水飞蓟宾控释制剂的制备及释放机制研究[J]. 中草药, 2015(08):1145-1150.
1. 徐静涵, 薛芸, 王彦,等. 核壳型色谱柱-高效液相色谱法快速分离检测水飞蓟素中7种非对映异构体[J]. 化学与生物工程, 2017, 06(v.33;No.222):69-74.
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