- ￥900 - 2000
- Solarbio
- 北京
- IC2940
- 2025年07月23日
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- 详细信息
- 技术资料
- 保存条件：
Powder:-20℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year
- 保质期：
Powder:-20℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year
- 英文名：
Complanatoside A
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- CAS号：
146501-37-3
- 规格：
20mg/10mg/5mg
| 规格： | 20mg | 产品价格： | ￥2000.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥1320.0 |
| 规格： | 5mg | 产品价格： | ￥900.0 |
| 基本信息 | |
| CAS | No.146501-37-3 |
| 中文名称 | 沙苑子苷 A |
| 英文名称 | Complanatoside A |
| 分子式 | C27H30O18 |
| 分子量 | 642.52 |
| 溶解性 | Soluble in DMSO ≥1mg/mL |
| 纯度 | ≥98% |
| 外观(性状) | Solid |
| 储存条件 | Powder:-20℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year |
| SMILES | O=C1C(O[C@@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO)=C(C3=CC(O)=C(O[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO)C(O)=C3)OC5=CC(O)=CC(O)=C15 |
| 靶点 | Others |
| 通路 | Others |
| 背景说明 | 是一种存在于沙苑子中的一种黄酮苷,具有生物或化学活性。 |
| In Vitro | A simple and sensitive LC-MS/MS method is developed for the determination of complanatoside A in rat plasma over the range of 2.3–575 ng/mL. Complanatoside A is extracted from plasma by a protein precipitation procedure，separated by LC and detected by MS/MS in positive electrospray ionization mode. The lower limit of quantification is established at 2.3 ng/mL. Intra- and inter-day precisions(LLOQ，low-QC，med-QC and high-QC)are less than 7.9%，and accuracies are between 94.0 and 105.1%. Matrix effect is acceptable(97.9–103.0%)and extraction recovery is reproducible(88.5–94.4%). Complanatoside A is stable in the investigated conditions. The method is applied to the pharmacokinetics of complanatoside A in rats[1]. |
| 动物实验 | The assay was applied to determine the concentrations of complanatoside A in plasma samples collected from a pharmacokinetic study in rats. Six healthy male Sprague–Dawley rats(200–230 g)were used for the pharmacokinetic study. The rats were housed and handled as reported previously(Guo et al.，2015). The rats were fasted for 12 h before the experiment. Complanatoside A was formulated in water and a single dose of 30 mg/kg was administered by oral gavage. Blood samples were obtained from the vena orbitalis just prior to dose and at 0.083，0.167，0.25，0.5，0.75，1，2，3，5，7，10 and 14 h after administration. After centrifuga_x0002_tion at 6000g for 10 min，the upper plasma was collected and stored at –20°C before analysis.[1] |
| 数据来源文献 | [1]. Li N， et al. Quantification of complanatoside A in rat plasma using LC-MS/MS and its application to a pharmacokinetic study. Biomed Chromatogr. 2016 Jun;30(6):888-93. |
| 单位 | 瓶 |
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IC2940 沙苑子苷 A 抑制剂/拮抗剂/激动剂 索莱宝
￥900 - 2000
