GUANOSINE 5-MONOPHOSPHATE, PER

Two‐Step, One‐Pot Synthesis of Inosine, Guanosine, and 2′‐Deoxyguanosine O6‐Ethers via Intermediate O6‐(Benzotriazol‐1‐yl) Derivatives

for the etherification at the O 6 ?position of silyl?protected inosine, guanosine, and 2??deoxyguanosine is described. Typically, a THF solution of the silylated nucleoside is treated with 1H ?benzotriazol?1?yloxy?tris(dimethylamino)phosphonium hexafluorophosphate (BOP

Measurement of Second Messengers in Signal Transduction: cAMP and Inositol Phosphates

., Kalinka, S., Cushing, A., Kitcher, J.P., O'Sullivan, M.J., and Baxendale, P.M. 1992. Enzyme immunoassays for the estimation of adenosine 3′,5′‐cyclic monophosphate and guanosine 3′,5′‐cyclic monophosphate in biological fluids. J. Immunol. Methods 155:31‐40

Biotinylation of a Propargylated Cyclic (3′‐5′) Diguanylic Acid and of Its Mono‐6‐Thioated Analog Under “Click” Conditions

?isobutyryl?5??O ?(4,4??dimethoxytrityl)?2??O ?(propargyl)guanosine is converted to its 3??O ?levulinyl ester in a yield of 91%. The reaction of commercial N 2 ?isobutyryl?5??O ?(4,4??dimethoxytrityl)?2??O ?tert ?butyldimethylsilyl?3??O ?[(2?cyanoethyl)?N ,N