5-Fluoro-4-Hydroxy-2-(Methylth

Crystallographic Analyses of Chemically Synthesized Modified Hammerhead RNA Sequences as a General Approach Toward Understanding Ribozyme Structure an

of the ribozyme can only be accomplished by using the chemical synthesis approach. Many “unnatural” hammerhead RNA sequence modifications, including modified purine and pyrimidine bases, 2′-fluoro- and 2′-amino-modified riboses, and phosphorothioates

Release of DNA Oligonucleotides and Their Conjugates from Controlled‐Pore Glass Under Thermolytic Conditions

of oligodeoxyribonucleotides. J. Org. Chem. 68:10123‐10129.    Cieślak, J., Grajkowski, A., Livengood, V., and Beaucage, S.L. 2004. The thermolytic 4‐methylthio‐1‐butyl group for phosphate