3-Pyridinecarboxamide, 6-chlor
o-N-[4-[[[2-(methylamino)-4-quinazolinyl]amino]methyl]phenyl]-- 询价
- ITI Biochem
- 美国
- 1039731-99-1
- 2025年07月17日
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- 文献和实验
- 技术资料
- 英文名：
3-Pyridinecarboxamide, 6-chloro-N-[4-[[[2-(methylamino)-4-quinazolinyl]amino]methyl]phenyl]-
- 库存：
98
- 供应商：
北京孚博
- CAS号：
1039731-99-1
- 规格：
1g
CAS：1039731-99-1
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文献和实验Synthesis of 3-Amino-l-CarboxymethyI-Benzodiazepine (BZA) Peptidomimetics
inhibitors of Ras famesyltransferase (FTase) (6 ,7 ). The central pair of amino acids in the CAAX tetrapeptide was replaced with the nonpeptide scaffold 3-methylamino-1-carboxymethyl-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one, (N -Me)BZA, shown below.
-4-sulfonate (15 ,16 ), methyl 4-(6-methoxynaphthalene-2-yl)-4-oxo-2-butenoate (17 ), N-(1-pyrenyl)maleimide (18 ), monobromobimane (19 –23 ), o -phthaldialdehyde (24 ,25 ), 9-fluorenylmethyloxycarbonyl chloride (26 ), and 2-chloro-1-methylpyridinium
Expression and Purification of Recombinant -Defensins and -Defensin Precursors in Escherichia coli
by centrifugation are lysed in 6 M guanidine-HCl under non-reducing conditions, the expressed defensin fused to its 6xHis-34 amino acid N-terminal fusion partner is purified by affinity chromatography on nickel-NTA columns. A Met codon introduced at the N terminus
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