1,4-di-(1H-Benzo[d]imidazol-2-

Biotinylation of a Propargylated Cyclic (3′‐5′) Diguanylic Acid and of Its Mono‐6‐Thioated Analog Under “Click” Conditions

of the propargylated c‐di‐GMP 9 from the propargylated dinucleoside phosphate triester 5 . Abbreviations: GiBu , 2‐( N ‐isobutyryl)guanin‐9‐yl; TBDMS, tert ‐butyldimethylsilyl; Gua, guanin‐9‐yl. Adapted with permission from Grajkowski et al. (). Copyright 2010 American

Convenient and Efficient Approach to the Permanent or Reversible Conjugation of RNA and DNA Sequences with Functional Groups

Figure 4.52.1 Synthesis of 2′‐ O ‐(aminooxymethyl)ribonucleosides (S.5 a‐d ). Abbreviations: BP , a uracil‐1‐yl, b N 4 ‐benzoylctytosin‐1‐yl, c N 6 ‐isobutyryladenin‐9‐yl, d N 2 ‐phenoxyacetylguanin‐9‐yl; DBU, 1,8‐diazabicyclo[5.4.0]undec‐7‐ene; B

Release of DNA Oligonucleotides and Their Conjugates from Controlled‐Pore Glass Under Thermolytic Conditions

) 0.25 M 5‐ethylthio‐1H ‐tetrazole in dry acetonitrile (ETT/MeCN; Glen Research) 3H ‐1,2‐Benzodithiol‐3‐one 1,1‐dioxide (Glen Research