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- 技术资料
- 免疫原:
catenin(cadherin-associated protein), beta 1, 88kDa
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB, IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
catenin(cadherin-associated protein), beta 1, 88kDa
- 抗体英文名:
CTNNB1 antibody
- 抗体名:
CTNNB1 antibody
- 规格:
100μl
CTNNB1 antibody
Product Name CTNNB1 antibody
Catalog No PAab09998
Packing 100ul
Form liquid
Alternative Name b cat, Beta catenin, beta-Catenin, Catenin beta 1, CTNNB, CTNNB1, PRO2286, β catenin, β-catenin
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.
Immunogen catenin(cadherin-associated protein), beta 1, 88kDa
Specificity Human, Mouse
Tested Application ELISA, WB, IHC
Recommended dilution WB: 1:500-1:2000; IHC: 1:20-1:200
IHC use Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab09998(CTNNB1 Antibody) at dilution of 1:200
WB use
mouse heart tissue were subjected to SDS PAGE followed by western blot with PAab09998(CTNNB1 antibody) at dilution of 1:1000
Protein Information
Gene ID 1499
Uniprot ID P35222
Calculated MW 90 kDa
Research Area Signal Transduction, Cardiovascular, Immunology, Cancer, Stem Cells, Neuroscience
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