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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
ATP2A2
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB, IHC, IF
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
ATP2A2
- 抗体英文名:
ATP2A2 antibody
- 抗体名:
ATP2A2 antibody
- 规格:
100μl
ATP2A2 antibody
Product Name ATP2A2 antibody
Catalog No PAab09918
Packing 100ul
Form liquid
Alternative Name ATP2B, DAR, DD, SERCA2
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen ATP2A2
Specificity Human, Mouse, Rat
Tested Application ELISA, WB, IHC, IF
Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
IHC use Immunohistochemistry of paraffin-embedded mouse brain using PAab09918(ATP2A2 antibody) at dilution of 1:100
WB use
MCF7 cells were subjected to SDS PAGE followed by western blot with PAab09918(ATP2A2 Antibody) at dilution of 1:1000
Protein Information
Gene ID 488
Uniprot ID P16615
Calculated MW 110 kDa
Research Area
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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