- ￥2260
- LSM Bio
- 进口
- PAab09891
- 2025年07月15日
- ELISA, IHC, WB
- E. coli - derived recombinant protein
- Human, Mouse, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
synuclein, alpha (non A4 component of amyloid precursor)
- 亚型：
IgG1
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
monoclonal
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse, Rat
- 保质期：
6个月
- 抗原来源：
Mouse
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA, IHC, WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
synuclein, alpha (non A4 component of amyloid precursor)
- 抗体英文名：
alpha-synuclein antibody
- 抗体名：
alpha-synuclein antibody
- 规格：
100μl
alpha-synuclein antibody
Product Name alpha-synuclein antibody
Catalog No PAab09891
Packing 100ul
Form liquid
Alternative Name Alpha synuclein, NACP, PARK1, PARK4, SNCA
Purification protein A+G purified
Purity 95% as determined by SDS-PAGE
Host Mouse
Isotype IgG1
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Immunogen synuclein, alpha (non A4 component of amyloid precursor)
Specificity Human, Mouse, Rat
Tested Application ELISA, IHC, WB
Recommended dilution WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000
IHC use Immunohistochemistry of paraffin-embedded mouse brain using PAab09891(SNCA antibody) at dilution of 1:1000
WB use
mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab09891(SNCA antibody) at dilution of 1:1000
Protein Information
Gene ID 6622
Uniprot ID P37840
Calculated MW 23 kDa
Research Area Neuroscience
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文献和实验【求助】请问alpha-synuclein的等电点是多少呢？
pophjp 请问alpha-synuclein的等电点是多少呢？不胜感激~-~ Fasta921 pophjp wrote: 请问alpha-synuclein的等电点是多少呢？不胜感激~-~ http://expasy.org/tools/pi_tool.html 输入你蛋白的氨基酸序列就知道PI pophjp
Adult transgenic fruit flies (Drosophila melanogaster ) carrying the human gene coding for the protein α-synuclein were tested for geotactic, locomotor, and phototactic behaviors as well as α-synuclein expression. Specific assays in adult
【求助】矛盾的实验结果：IKb alpha和NFKB同时升高
吴佰霖 我的基因过表达，结合文献，推理应该是IKb alpha下降，而NFKB升高 （IKb可磷酸化NFKB，使后者降低） 但现在我的结果是两者同时升高，请问可能的原因有哪些呢？ 谢谢 woxingwosu 可否检测一下NFKB的磷酸化情况？ erik NFKB是检测核内的吗？检测p65还是p50/ 吴佰霖 检测总蛋白
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