- ￥2260
- LSM Bio
- 进口
- PAab09852
- 2025年07月14日
- ELISA, WB, IHC, IF, IP
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
angiomotin
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA, WB, IHC, IF, IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
angiomotin
- 抗体英文名：
AMOT antibody
- 抗体名：
AMOT antibody
- 规格：
100μl
AMOT antibody
Product Name AMOT antibody
Catalog No PAab09852
Packing 100ul
Form liquid
Alternative Name AMOT, angiomotin, KIAA1071
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Angiomotin belongs to the motin family of angiostatin binding protein. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Most abundant expression was found in placenta and skeletal muscle. AMOT has two isoforms with MW 130 kDa (p130) and 80 kDa (p80). The p130 isoform can interact with F-actin.This antibody recognizes both p130 and p80.
Immunogen angiomotin
Specificity Human
Tested Application ELISA, WB, IHC, IF, IP
Recommended dilution WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200
IHC use Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using PAab09852(AMOT Antibody) at dilution of 1:200
WB use
HEK293 cells were subjected to SDS PAGE followed by western blot with PAab09852(AMOT Antibody) at dilution of 1:1000
Protein Information
Gene ID 154796
Uniprot ID Q4VCS5
Calculated MW 62 kDa
Research Area Cardiovascular, Developmental biology
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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