- ￥2260
- LSM Bio
- 进口
- PAab10115
- 2025年07月15日
- ELISA, WB, IF, IHC
- E. coli - derived recombinant protein
- Human, Mouse, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TNF receptor-associated factor 2
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse, Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA, WB, IF, IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
TNF receptor-associated factor 2
- 抗体英文名：
TRAF2 antibody
- 抗体名：
TRAF2 antibody
- 规格：
100μl
TRAF2 antibody
Product Name TRAF2 antibody
Catalog No PAab10115
Packing 100ul
Form liquid
Alternative Name TRAF2, TRAP, TRAP3
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.
Immunogen TNF receptor-associated factor 2
Specificity Human, Mouse, Rat
Tested Application ELISA, WB, IF, IHC
Recommended dilution WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
IHC use Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using PAab10115( TRAF2 Antibody) at dilution of 1:200
WB use
HeLa cells were subjected to SDS PAGE followed by western blot with PAab10115 (TRAF2 antibody) at dilution of 1:1000
Protein Information
Gene ID 7186
Uniprot ID Q12933
Calculated MW 54 kDa
Research Area Epigenetics, Signal Transduction, Metabolism
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