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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
PRKCQ
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
PRKCQ
- 抗体英文名:
PRKCQ antibody
- 抗体名:
PRKCQ antibody
- 规格:
100μl
PRKCQ antibody
Product Name PRKCQ antibody
Catalog No PAab10092
Packing 100ul
Form liquid
Alternative Name PRKCQ, PRKCT, nPKC-theta, protein kinase C theta
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.
Immunogen PRKCQ
Specificity Human
Tested Application ELISA, IHC
Recommended dilution IHC: 1:50 - 1:200
IHC use Immunohistochemistry of paraffin-embedded human colon cancer using PAab10092(PRKCQ antibody) at dilution of 1:50
WB use
Protein Information
Gene ID 5588
Uniprot ID Q04759
Calculated MW 85 kDa
Research Area Cell Division and Proliferation, Signal Transduction, Metabolism, cancer, Immunology
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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