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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Kruppel-like factor 4 (gut)
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
Kruppel-like factor 4 (gut)
- 抗体英文名:
KLF4 antibody
- 抗体名:
KLF4 antibody
- 规格:
100μl
KLF4 antibody
Product Name KLF4 antibody
Catalog No PAab10038
Packing 100ul
Form liquid
Alternative Name EZF, GKLF, KLF4
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen Kruppel-like factor 4 (gut)
Specificity Human
Tested Application ELISA, WB
Recommended dilution WB: 1:200-1:2000
IHC use
WB use
HeLa cells were subjected to SDS PAGE followed by western blot with PAab10038(KLF4 antibody) at dilution of 1:1000
Protein Information
Gene ID 9314
Uniprot ID O43474
Calculated MW 50 kDa
Research Area Metabolism, Cardiovascular, Developmental biology, Neuroscience, Stem Cells
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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